刘国生 研究员 (百人、杰青)

中国科学院上海有机化学研究所

金属有机化学国家重点实验室 

上海市零陵路345号,200032

电话: +86 21 54925346

传真: +86 21 64166128

邮箱: gliu@sioc.ac.cn

主页:http://guoshengliu.sioc.ac.cn

教育:

1999.09 - 2002.07  中国科学院上海有机化学研究所,理学博士(导师:陆熙炎院士)

1996.09 - 1999.09  中国科学院大连化学物理研究所,理学硕士(导师:郑卓研究员)

1991.09 - 1995.07  南京理工大学化工学院,工科学士

工作经历:

2007.08 -      中国科学院上海有机化学研究金属有机国家重点实验室,研究员

2005.08 - 2007.07  Postdoctoral fellow, University of Wisconsin-Madison (Prof. Shannon S. Stahl)

2003.04 - 2005.07  Visiting Scientist, Lehigh University(Prof.Li. Jia)

2002.09 - 2003.03  项目主管,晟康(上海)国际生物有限公司

1995.08 - 1996.08  技术员,江西长江化工厂

研究领域:

过渡金属催化的高选择性反应研究

  • C-H 键活化及官能化
  • C-F键形成及其相关反应
  • 反应机理研究
  • 新型可降解高分子材料的合成

职务:

课题组长

代表论著:

1. Yin, Guoyin;Wu, Yichen;Liu,Guosheng* “Scope and Mechanism of Allylic C-H Amination of Terminal Alkenes by the Palladium/PhI(OPiv)2 Catalyst System: Insights into the Effect of Naphthoquinone”, J. Am. Chem. Soc. 2010, 132, 11978-11987.

2. Qiu, Shuifa; Xu, Tao; Zhou, Juan; Guo, Yanlong; Liu, Guosheng* “Palladium-Catalyzed Intermolecular Aminofluorination of Styrenes”, J. Am. Chem. Soc. 2010, 132, 2856-2857.

3. Wu, Tao; Yin, Guoyin; Liu, Guosheng* “Palladium-Catalyzed Intramolecular Aminofluorination of Unactivated Alkenes”, J. Am. Chem. Soc. 2009, 131, 16354-16355.

4. Wu, Liang; Qiu, Shuifa; Liu, Guosheng* “Brønsted Base-Modulated Regioselective Pd-Catalyzed Intramolecular Aerobic Oxidative Amination of Alkenes:Formation of Seven-Membered Amides and Evidence for Allylic C-H Activation.” Org. Lett. 2009, 11, 2707-2710.

5. Qiu, Shuifa; Wei, Yunyang; Liu, Guosheng* “Palladium-Catalyzed Intramolecular Hydro- amination of Allenes Coupled to Aerobic Alcohol Oxidation.” Chem. Eur. J. 2009, 15, 2751-2754.

6. Liu, Guosheng;* Yin, Guoyin; Wu, Liang; “Palladium-catalyzed intermolecular aerobic oxidative amination of terminal alkenes: efficient synthesis of linear allylamine derivatives.” Angew. Chem. Int. Ed. 2008, 47, 4733-4736.

7. Yin, Guoyin; Liu, Guosheng* “Palladium-catalyzed oxidative cyclization of enyne with hydrogen peroxide as the oxidant.” Angew. Chem. Int. Ed. 2008, 47, 5442-5445. (Featured in Synfact, 2008, 10, 1066)

8. Wu, Yicheng; Liu, Guosheng* “Palladium-Catalyzed Allylic C-H Bond Functionalization of Olefins”, Top. Cur. Chem. 2010, 292, 195-209.

9. Liu, Guosheng; Stahl, Shannon. S* “Two-Faced Reactivity of Alkenes: cis- versus trans-aminopalladation in Aerobic Pd-Catalyzed Intramolecular Aza-Wacker Reactions.” J. Am. Chem. Soc. 2007, 129, 6328-6335.

10. Liu, Guosheng; Stahl, Shannon. S* “Highly Regeioselective Pd-Catalyzed Intermolecular Aminoacetoxylation of Alkene and Evidence for the cis-Aminopalladation and SN2 C-O Bond Formation”, J. Am. Chem. Soc. 2006, 128,7179-7181.

11. Liu, Guosheng; Jia, Li* “Cobalt-Catalyzed Carbonylative Copolymerizaiton of N-Alkylazetidines and Tetrahydrofuran”, Angw. Chem. Int. Ed. 2006, 45,129-131.

12. Liu, Guosheng; Jia, Li* “Design of Catalytic Carbonylative Polymerizations of Heterocylces. Synthesis of Polyesters and Amphiphilic Poly(amide-block-ester)s”, J. Am. Chem. Soc. 2004, 126, 14716.