刘元红 研究员 

中国科学院上海有机化学研究所

金属有机化学国家重点实验室 

上海市零陵路345号,200032

电话: +86 21 54925135

传真: +86 21 64166128

邮箱: yhliu@sioc.ac.cn

 

教育:

1988.9 - 1992.7   郑州大学化学系,学士

1992.9 - 1995.7   郑州大学化学系,硕士

1997.4 - 2000.3   日本北海道大学药学部,博士 (导师:Prof. Tamotsu Takahashi)

工作经历:

2000.4 - 2000.12   日本北海道大学催化研究中心,日本学术振兴学会(JSPS)特别研究员

2001.1 - 2002.12   日本北海道大学催化研究中心,COE(center of excellence)研究员

2003.1 - 2003.9  日本北海道大学催化研究中心,博士后研究员

2003.10 - 现在   中科院上海有机化学研究所,研究员

研究领域:

  1. 金催化的高效串联反应:利用金催化的策略,发展基于官能团化的炔烃等分子体系的高效串联反应,实现具有潜在生物活性的碳环和杂环分子的合成。 

  2. 廉价金属镍催化的反应方法学研究:实现镍催化惰性C-X键的断裂与偶联反应,发展镍催化的基于烯烃或炔烃的转化反应新模式。 

  3. 有机硼化合物的合成及反应性能研究:发展过渡金属催化的有机硼化合物的合成新方法,探索有机硼化合物在偶联等反应中的应用。 

获奖及荣誉:

  • Thieme Chemistry Journals Award (2007)
  • The Distinguished Lectureship Award from The Chemical Society of Japan (2007)

职务:

课题组长

 

主要研究进展:

  1. 金催化的高效串联反应 

  利用金易于活化炔烃、烯烃和联烯,在反应中易于形成碳正离子、金卡宾等特点,集中探索金催化的各类串联反应如扩环反应,1,6-卡宾迁移反应以及偶联反应等,发展实用有效的有机合成新方法。 

 

  

    2. 廉价金属镍催化的反应方法学研究 

  镍存在较多的氧化态,在反应过程中存在多种价态的循环过程,且易于通过形成丰富的金属中间体如金属杂环、烯基镍等实现炔烃的转化反应。我们开展了涉及惰性C-X键的偶联反应及炔烃的官能团化反应等。 

 

  

    3. 有机硼化合物的合成及反应性能研究 

  利用过渡金属催化的硼化反应与其它反应相结合,开展含硼产物尤其是环化产物的合成等。 

 

代表论著:

1. Nickel-Catalyzed Highly Regioselective Hydrocyanation of Terminal Alkynes with Zn(CN)2 Using Water as the Hydrogen Source. Xingjie Zhang, Xin Xie, and Yuanhong Liu* J. Am. Chem. Soc. 2018, 140, 7385. 

2. Gold(I)-Catalyzed Formal Intramolecular Dehydro-Diels?Alder Reaction of Ynamide-ynes: Synthesis of Functionalized Benzo[b]carbazoles. Wei Xu, Gaonan Wang, Xin Xie, and Yuanhong Liu* Org. Lett. 2018, 20, 3273. 

3. Copper-Catalyzed Borylative Cyclization of o?(Cyano)phenyl Propargyl Carbonates: Synthesis of Functionalized 1?Naphthylamines. Meijun Xiong,? Hui Hu,? Xiaoping Hu, and Yuanhong Liu* Org. Lett. 2018, 20, 3661. 

4. Gold-Catalyzed Oxidative Cyclizations of {o?(Alkynyl)phenyl propargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration: Synthesis of Functionalized 1H?Isochromenes and 2H?Pyrans. Jidong Zhao, Wei Xu, Xin Xie, Ning Sun, Xiangdong Li, and Yuanhong Liu* Org. Lett. 2018, DOI: 10.1021/acs.orglett.8b02380.

5. Ligand-Effect in Gold(I)-Catalyzed Rautenstrauch Rearrangement: Regio- and Stereoselective Synthesis of Bicyclo[3.2.1]octa-3,6-dienes through Cyclodimerization of 1-Ethynyl-2-propenyl Esters. Jidong Zhao, Shuang Yang, Xin Xie, Xiangdong Li, and Yuanhong Liu* J. Org. Chem. 2018, 83, 1287. 

6. PBr3-Mediated Cyclization of 1,7-Diyn-3,6-bis(propargyl carbonate)s: Synthesis of 5-BromotetracenesNing Sun, Haoyi Chen, Xiangdong Li, Murong Xu, Yi Gan, Liangwei Zhang, and Yuanhong Liu* J. Org. Chem. 2017, 82, 10051. 

7. Synthesis of functionalized indolizines via gold(I)-catalyzed intramolecular hydroarylation/aromatization of pyrrole-ynes, Xiangdong Li, Jidong Zhao, Xin Xie and Yuanhong Liu * Org. Biomol. Chem., 2017, 15, 8119. 

8. Gold-Catalyzed Cadiot-Chodkiewicz-type Cross-Coupling of Terminal Alkynes with Alkynyl Hypervalent Iodine Reagents: Highly Selective Synthesis of Unsymmetrical 1,3-Diynes. Xiangdong Li, Xin Xie, Ning Sun, and Yuanhong Liu* Angew. Chem. Int. Ed. 2017, 56, 6994.

9. Synthesis of δ- and α-Carbolines via Nickel-Catalyzed [2+2+2] Cycloaddition of Functionalized Alkyne-Nitriles with Alkynes. Gaonan Wang, Xu You, Yi Gan, and Yuanhong Liu* Org. Lett. 2017, 19, 110. 

10. General and Mild Nickel-Catalyzed Cyanation of Aryl/Heteroaryl Chlorides with Zn(CN)2 : Key Roles of DMAP. Xingjie Zhang, Aiyou Xia, Haoyi Chen, and Yuanhong Liu* Org. Lett. 2017, 19, 2118. 

11. Gold-Catalyzed Formal [3+2] Cycloaddition of Ynamides with 4,5-Dihydro-1,2,4-oxadiazoles: Synthesis of Functionalized 4-Aminoimidazoles. Wei Xu, Gaonan Wang, Ning Sun, and Yuanhong Liu* Org. Lett. 2017, 19, 3307. 

12. Copper-Catalyzed Borylative Cyclization of in Situ Generated o?Allenylaryl Nitriles with Bis(pinacolato)diboron. Meijun Xiong, Xin Xie, and Yuanhong Liu* Org. Lett. 2017, DOI: 10.1021/acs.orglett.7b01355. 

13. Base-Catalyzed Cyclization of 1,6-Diynyl Carboxylates Involving Propargyl-Allenyl Isomerization: Efficient Synthesis of Benzo[b] fluorene and Its Analogues. Ning Sun, Xin Xie, Gaonan Wang, Haoyi Chen, and Yuanhong Liu* Adv. Synth. Catal. 2017, 359, 1394. 

14. Nickel-Catalyzed [2++2+2] Cycloaddition of Alkyne-Nitriles with Alkynes Assisted by Lewis Acids: Efficient Synthesis of Fused Pyridines. Xu You, Xin Xie, Gaonan Wang, Meijun Xiong, Renhong Sun, Haoyi Chen, and Yuanhong Liu* Chem. Eur. J. 2016, 22, 16765.  

15. Gold-Catalyzed Cyclization of Furan-Ynes bearing a Propargyl Carbonate Group: Intramolecular Diels–Alder Reaction with In Situ Generated Allenes. Ning Sun, Xin Xie, Haoyi Chen, and Yuanhong Liu* Chem. Eur. J. 2016, 22, 14175. 

16. Gold(I)-Catalyzed Cascade Hydroarylation/Cycloaromatization to Indolizines via Pyridine Ring Construction. Xiangdong Li, Xin Xie, and Yuanhong Liu* J. Org. Chem. 2016, 81, 3688. 

17. Dioxazoles, a new mild nitrene transfer in gold catalysis: highly efficient synthesis of functionalized oxazoles. Ming Chen, Ning Sun, Haoyi Chen and Yuanhong Liu* Chem. Commun., 2016, 52, 6324. 

18. Nickel-catalyzed cyclization of alkyne-nitriles with organoboronic acids involving anticarbometalation of alkynes. Xingjie Zhang, Xin Xie and Yuanhong Liu* Chem. Sci., 2016, 7, 5815. 

19. Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic C–H functionalization. Wei Xu, Ming Chen, Ning Sun and Yuanhong Liu* Chem. Commun., 2016, 52, 11000. 

20. Gold-Catalyzed Synthesis of Tropone and Its Analogues via Oxidative Ring Expansion of Alkynyl Quinols. Jidong Zhao, Jun Liu, Xin Xie, Shi Li,* and Yuanhong Liu* Org. Lett. 2015, 17, 5926. 

21. Cyano-Schmittel Cyclization through Base-Induced Propargyl-Allenyl Isomerization: Highly Modular Synthesis of Pyridine-Fused Aromatic Derivatives. Xu You, Xin Xie, Haoyi Chen, Yuxue Li,* and Yuanhong Liu* Chem. Eur. J. 2015, 21, 18699. 

22. Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic CarbonHeteroatom Bond. Ming Chen, Ning Sun, Wei Xu, Jidong Zhao, Gaonan Wang, and Yuanhong Liu* Chem. Eur. J. 2015, 21, 18571. 

23. Reactions of Zirconocene1-Aza-1,3-diene Complexes with Acyl Cyanides: Substrate-Dependent Synthesis of Acyl- or Non-Acyl-Substituted Pyrroles. Meijun Xiong, Shasha Yu, Xin Xie, Shi Li, and Yuanhong Liu* Organometallics 2015, 34, 5597. 

24. Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines, Renhong Sun, Jun Liu, Shuang Yang, Ming Chen, Ning Sun, Haoyi Chen, Xin Xie, Xu You, Shi Li and Yuanhong Liu* Chem. Commun., 2015, 51, 6426. 

25. Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade. Liangwei Zhang,ab Xiangdong Li,b Yuanhong Liu*b and Dayong Zhang, *Chem. Commun., 2015, 51, 6633. 中国药科大学为第一单位. 

26. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade, Xiangdong Li, Ming Chen, Xin Xie, Ning Sun, Shi Li,* and Yuanhong Liu* Org. Lett. 2015, 17, 2984. 

27. Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridines or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds Ming Chen, Yifeng Chen, Ning Sun, Jidong Zhao, Yuanhong Liu* and Yuxue Li* Angew. Chem. Int. Ed. 2015, 54, 1200. 

28. Gold(I)-Catalyzed 1,2-Acyloxy Migration/[3+2] Cycloaddition of 1,6-Diynes with an Ynamide Propargyl Ester Moiety: Highly Efficient Synthesis of Functionalized Cyclopenta[b]indoles Jun Liu, Ming Chen, Liangwei Zhang, Yuanhong Liu* Chem. Eur. J. 2015, 21, 1009. 

29. Zirconium-Mediated Multicomponent Reactions of 1,3-Butadiynes with Ylidenemalononitriles to Form Functionalized 1,8-Naphthyridine and Cyclopenta[b]pyridine Derivatives Shasha Yu, Renhong Sun, Haoyi Chen, Xin Xie, and Yuanhong Liu* Chem. Eur. J. 2015, 21, 1420. 

30. Gold(I)-Catalyzed 1,4 and/or 1,5-Heteroaryl Migration Reactions via Regiocontrolled Cyclizations Chengyu Wang, Xin Xie, Jun Liu, Yuanhong Liu* and Yuxue Li* Chem. Eur. J. 2015, 21, 559. 

31. Insertion of Nitriles into Zirconocene-1-aza-1,3-diene Complexes: Chemoselective Synthesis of N-H and N-Substituted Pyrroles. Shasha Yu, Meijun Xiong, Xin Xie, and Yuanhong Liu*Angew. Chem. Int. Ed. 2014, 53, 11596. 

32. Titanium-mediated Cross-coupling Reactions of 1,3-butadiynes with α-iminonitriles to 3-aminopyrroles: Observation of an Imino aza-Nazarov Cyclization Xu You, Xin Xie, Renhong Sun, Haoyi Chen, Shi Li and Yuanhong Liu* Org. Chem. Front., 2014, 1, 940.  

33. Gold(I)-Catalyzed Furan-yne Cyclizations Involving 1,2-Rearrangement: Efficient Synthesis of Functionalized 1-Naphthols and Its Application to the Synthesis of Wailupemycin G. Yifeng Chen, Lu Wang, Ning Sun, Xin Xie, Xiaobo Zhou, Haoyi Chen, Yuxue Li,* and Yuanhong Liu* Chem. Eur. J. 2014, 20, 12015. 

34. Gold-Catalyzed Cascade Reactions of Furan-ynes with External Nucleophiles Consisting of  1,2-Rearrangement: Straightforward Synthesis of Multi-Substituted Benzo[b]furans. Ning Sun, Xin Xie, and Yuanhong Liu* Chem. Eur. J. 2014, 20, 7514. 

35. Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes. Ning Sun, Ming Chen, and Yuanhong Liu* J. Org. Chem. 2014, 79, 4055. 

36. Titanium-mediated reductive cross-coupling reactions of imines with nitriles: an efficient route for the synthesis of a-aminoketones or 1,2-diketones Haoyi Chen, Guoqin Fan, Shi Li, Kebin Mao, Yuanhong Liu* Tetrahedron Letters, 2014, 55, 1593. 

37. Gold-Catalyzed Oxidative Rearrangement Involving 1,2-Acyl Migration: Efficient Synthesis of Functionalized Dihydro-γ-Carbolines from α-(2-Indolyl) Propargylic Alcohols and Imines, Lu Wang, Xin Xie, Yuanhong Liu* Angew. Chem. Int. Ed. 2013, 52, 13302. 

38. Gold-catalyzed cascade cycloisomerization of 1,7-diyn-3,6-bis(propargyl carbonate)s. Stereoselective synthesis of naphtho[b]cyclobutenes, Chen Ming, Liu, Jun, Wang Lu, Xiaobo Zhou, Yuanhong Liu* Chem. Commun., 2013, 49, 8650. 

39. Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl)stannanes, Liu Jun, Xin Xie, Yuanhong Liu* Chem. Commun., 2013, 49, 11794. 

40. Environmentally Benign Synthesis of Indeno[1,2-b]quinolines via an Intramolecular Povarov Reaction, Chen Ming, Ning Sun, Yuanhong Liu* Org. Lett. 2013, 15, 5574. 

41. Unusual Regioselectivity in the Aldehyde Addition Reactions of Allenyl/Propargyl Zirconium Complexes Derived from γ-(2-Pyridyl)propargyl Ethers: Synthesis of Multisubstituted α-Hydroxyallenes, Guoqin Fan, Xin Xie, Yuanhong Liu*, Yuxue Li*, Organometallics, 2013, 36, 1636. 

42. Reactions of Zirconocene Butadiyne or Monoyne Complexes with Nitriles: Straightfoward Synthesis of Functionalized Pyrimidines, Xu You, Shasha Yu, Yuanhong Liu* Organometallics, 2013, 32, 5273. 

43. Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: an efficient route for the synthesis of stereodefined allylic aminesMao Kebin, Guoqin Fan, Yuanhong Liu*, Shi Li, You Xu, Liu Dan, Beilstein J. Org. Chem., 2013, 9, 621. 

44.  -苯炔参与的金属杂环的形成及其在有机合成中的应用,毛可彬,付晓平,  刘丹*,李石,刘元红* 有机化学, 2013, 33, 780 

45. Palladium-catalyzed highly efficient synthesis of tetracenes and pentacenes. Ming Chen, Y. Chen, and Yuanhong Liu* Chem. Commun. 2012, 48, 12189.

46. Facile Synthesis of Fully Substituted Dihydro-β-carbolines via Br?nsted Acid Promoted Cascade Reactions of α-Indolyl Propargylic Alcohols with Nitrones. Lu Wang, Xin Xie, and Yuanhong Liu* Org. Lett. 2012, 14, 5848. 

47. Gold-Catalyzed Cyclization of 1,6-Diyne-4-en-3-ols: Stannyl Transfer from 2-Tributylstannylfuran Through Au/Sn Transmetalation, Yifeng Chen, Ming Chen, and Yuanhong Liu*. Angew. Chem. Int. Ed. 2012, 51, 6181.

48. Gold-Catalyzed Cascade Cyclizations of 1,6-Diynyl Carbonates to Benzo[b]fluorenes Involving Arylation of Oxocarbenium Ion Intermediates and Decarboxylative Etherification. Yifeng Chen, Ming Chen, and Yuanhong Liu*Angew. Chem. Int. Ed. 2012, 51, 6493.

49. Gold-Catalyzed Cyclizations of (o-Alkynyl)phenoxyacrylates with External Nucleophiles: Regio- and Stereoselective Synthesis of Functionalized Benzo[b]oxepines. Jun Liu, Yuanhong Liu* Org. Lett. 2012, 14,4742. 

50. Unexpected Multi-Component Reactions of Conjugated 1,3-Butadiynes or Monoynes with Acyl Cyanide Derivatives Mediated by Zirconium. Shasha Yu, Xu You, Yuanhong Liu* Chem. Eur. J. 2012, 18,13936. 

51. Nucleophilic Addition of Grignard Reagents to 3-Acylindoles: Stereoselective Synthesis of Highly Substituted Indoline Scaffolds. Lu Wang, Yushang Shao, and Yuanhong Liu*, Org. Lett. 2012, 14, 3978.

52. Highly Efficient Synthesis of cis-[3]Cumulenic Diols via Zirconocene-Mediated Coupling of 1,3-Butadiynes with Aldehydes, Xiaoping Fu, Shasha Yu, Guoqin Fan, Yuanhong Liu* and Yuxue Li, Organometallics 2012, 31, 531.

53. Gold-Catalyzed Furan/Yne Cyclizations for the Regiodefined Assembly of Multisubstituted Protected 1-Naphthols, Chengyu Wang, Yifeng Chen, Xin Xie, Jun Liu and Yuanhong Liu*, J. Org. Chem. 2012, 77, 1915?1921.

54. Titanium-Mediated Cross-Coupling Reactions of Imines with Ketones or Aldehydes: An Efficient Route for the Synthesis of 1,2-Amino Alcohols, Guoqin Fan and Yuanhong Liu, Tetrahedron Lett. 2012, 53, 5084. 

55. One-Pot Synthesis of Indole-Fused Scaffolds via Gold-Catalyzed Tandem Annulation Reactions of 1,2-Bis(alkynyl)-2-en-1-ones with Indoles, Xin Xie, Xiangwei Du, Yifeng Chen, and Yuanhong Liu*, J. Org. Chem. 2011, 76, 9175–9181.

56. Gold-Catalyzed Deacylative Cycloisomerization Reactions of 3-Acylindole/ynes: A New Approach for Carbazole Synthesis,Lu Wang, Guijie Li, and Yuanhong Liu*, Org. Lett. 2011, 13, 3786-3789.

57. Grignard Reagent Acceleration of the Intramolecular Diels-Alder Reaction of Furans with Unactivated Alkynes: Toward Structurally Complex Oxabicyclic Alkenes. Yifeng Chen, Lu Wang, Yuanhong Liu* and Yuxue Li*, Chem. Eur. J. 2011, 17, 12582.

58. Regio- and Stereoselective Construction of Highly Functionalized 3-Benzazepine Skeletons through Ring-Opening Cycloamination Reactions Catalyzed by Gold. Xiangwei Du, Shuang, Yang, Jingyu Yang and Yuanhong Liu*, Chem. Eur. J. 2011, 17, 4981-4985.

59. Gold-Catalyzed Approach to Multisubstituted Fulvenes via Cycloisomerization of Furan/Ynes, Yifeng Chen and Yuanhong Liu*, J. Org. Chem. 2011, 76, 5274.

60. Gold-Catalyzed Cascade Friedel-Crafts/Furan-Yne Cyclization/Heteroenyne Metathesis for the Highly Efficient Construction of Phenanthrene Derivatives. Yifeng Chen, Guijie Li and Yuanhong Liu*, Adv. Synth. Catal. 2011, 353, 392– 400.

61. Highly Efficient Synthesis of Multisubstituted 2-Acyl Furans via PIFA/I2 Mediated Oxidative Cycloisomerization of cis-2-En-4-yn-1-ols. Xiangwei Du, Haoyi Chen, Yifeng Chen, Jingjin Chen and Yuanhong Liu*, Synlett 2011, 1010.

62. Gold and Br?nsted Acid Catalyzed Isomerization of [3]Cumulenols and [3]Cumulenones: Efficient Syntheses of 1,5-Dien-3-ynes and Furan Derivatives. Erjuan Wang, Xiaoping Fu, Xin Xie, Jingjin Chen, Hongjun Gao and Yuanhong Liu*, Tetrahedron Lett. 2011, 52, 1968.

63. General and Mild Nickel-Catalyzed Cyanation of Aryl/Heteroaryl Chlorides with Zn(CN)2 : Key Roles of DMAP. Xingjie Zhang, Aiyou Xia, Haoyi Chen, and Yuanhong Liu* Org. Lett. 2017, 19, 2118. 

64. Gold-Catalyzed Formal [3+2] Cycloaddition of Ynamides with 4,5-Dihydro-1,2,4-oxadiazoles: Synthesis of Functionalized 4-Aminoimidazoles. Wei Xu, Gaonan Wang, Ning Sun, and Yuanhong Liu* Org. Lett. 2017, 19, 3307. 

65. Copper-Catalyzed Borylative Cyclization of in Situ Generated o?Allenylaryl Nitriles with Bis(pinacolato)diboron. Meijun Xiong, Xin Xie, and Yuanhong Liu* Org. Lett. 2017, DOI: 10.1021/acs.orglett.7b01355. 

66. Base-Catalyzed Cyclization of 1,6-Diynyl Carboxylates Involving Propargyl-Allenyl Isomerization: Efficient Synthesis of Benzo[b] fluorene and Its Analogues. Ning Sun, Xin Xie, Gaonan Wang, Haoyi Chen, and Yuanhong Liu* Adv. Synth. Catal. 2017, 359, 1394. 

67. Nickel-Catalyzed [2++2+2] Cycloaddition of Alkyne-Nitriles with Alkynes Assisted by Lewis Acids: Efficient Synthesis of Fused Pyridines. Xu You, Xin Xie, Gaonan Wang, Meijun Xiong, Renhong Sun, Haoyi Chen, and Yuanhong Liu* Chem. Eur. J. 2016, 22, 16765.  

68. Gold-Catalyzed Cyclization of Furan-Ynes bearing a Propargyl Carbonate Group: Intramolecular Diels–Alder Reaction with In Situ Generated Allenes. Ning Sun, Xin Xie, Haoyi Chen, and Yuanhong Liu* Chem. Eur. J. 2016, 22, 14175. 

69. Gold(I)-Catalyzed Cascade Hydroarylation/Cycloaromatization to Indolizines via Pyridine Ring Construction. Xiangdong Li, Xin Xie, and Yuanhong Liu* J. Org. Chem. 2016, 81, 3688. 

70. Dioxazoles, a new mild nitrene transfer in gold catalysis: highly efficient synthesis of functionalized oxazoles. Ming Chen, Ning Sun, Haoyi Chen and Yuanhong Liu* Chem. Commun., 2016, 52, 6324. 

71. Nickel-catalyzed cyclization of alkyne-nitriles with organoboronic acids involving anticarbometalation of alkynes. Xingjie Zhang, Xin Xie and Yuanhong Liu* Chem. Sci., 2016, 7, 5815. 

72. Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic C–H functionalization. Wei Xu, Ming Chen, Ning Sun and Yuanhong Liu* Chem. Commun., 2016, 52, 11000. 

73. Gold-Catalyzed Synthesis of Tropone and Its Analogues via Oxidative Ring Expansion of Alkynyl Quinols. Jidong Zhao, Jun Liu, Xin Xie, Shi Li,* and Yuanhong Liu* Org. Lett. 2015, 17, 5926. 

74. Cyano-Schmittel Cyclization through Base-Induced Propargyl-Allenyl Isomerization: Highly Modular Synthesis of Pyridine-Fused Aromatic Derivatives. Xu You, Xin Xie, Haoyi Chen, Yuxue Li,* and Yuanhong Liu* Chem. Eur. J. 2015, 21, 18699. 

75. Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic CarbonHeteroatom Bond. Ming Chen, Ning Sun, Wei Xu, Jidong Zhao, Gaonan Wang, and Yuanhong Liu* Chem. Eur. J. 2015, 21, 18571. 

76. Reactions of Zirconocene1-Aza-1,3-diene Complexes with Acyl Cyanides: Substrate-Dependent Synthesis of Acyl- or Non-Acyl-Substituted Pyrroles. Meijun Xiong, Shasha Yu, Xin Xie, Shi Li, and Yuanhong Liu* Organometallics 2015, 34, 5597. 

77. Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines, Renhong Sun, Jun Liu, Shuang Yang, Ming Chen, Ning Sun, Haoyi Chen, Xin Xie, Xu You, Shi Li and Yuanhong Liu* Chem. Commun., 2015, 51, 6426. 

78. Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade. Liangwei Zhang,ab Xiangdong Li,b Yuanhong Liu*b and Dayong Zhang, *Chem. Commun., 2015, 51, 6633. 中国药科大学为第一单位. 

79. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade, Xiangdong Li, Ming Chen, Xin Xie, Ning Sun, Shi Li,* and Yuanhong Liu* Org. Lett. 2015, 17, 2984. 

80. Highly Stereoselective Synthesis of Trisubstituted cis-[3]Cumulenols from Alkynylated Oxatitanacycles in the Presence of Lewis acids, Chen, J.; Liu,* Y. Organometallics 2010, 29, 505.

81. Gold-Catalyzed Cyclization of Alkynylaziridines as An Efficient Approach Toward Functionalized N-Phth Pyrroles. Xiangwei Du, Xin Xie and Yuanhong Liu*, J Org. Chem. 2010, 75, 510-513.

82. Gold-Catalyzed Benzannulation of 3-Alkoxy-1,5-enynes: Access to Functionalized Benzenes. Guijie Li and Yuanhong Liu*, J. Org. Chem. 2010, 75, 2903–2909.

83. Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives.Jingjin Chen, Guoqin Fan and Yuanhong Liu*, Org. Biomol. Chem. 2010, 8, 4806–4810.

84. 过渡金属催化的呋喃合成。卢玉华,宋飞杰,贾学顺*,刘元红*化学进展2010, 22, 58-70.

85. Gold-catalyzed Intramolecular Indole/Alkyne Cyclization Cascades through a Heterolytic Fragmentation: 1,5-Indole Migration and Allenylation, Li, G.; Liu,*Y. J. Org. Chem. 2010, 75, 3526.

86. Aldehyde Addition to 1,3-Butadiyne-Derived Zirconacyclocumulenes: Stereoselective Synthesis of cis-[3]Cumulenols, Fu, X.; Liu,* Y.;  Li*, Y. Organometallics 2010, 29, 3012.

87. Diverse Reactivity of Zirconacyclocumulenes Derived from Coupling of Benzynezirconocenes with 1,3-Butadiynes towards Acyl Cyanides: Synthesis of Indeno[2,1-b]pyrroles or [3]Cumulenones. Fu, X.; Chen, J.; Li, G.; Liu,* Y. Angew. Chem. Int. Ed. 2009, 48, 5500.

88. Gold-Catalyzed Cascade Friedel-Crafts/Furan-Alkyne Cycloisomerizations for the Highly Efficient Synthesis of Arylated (Z)-Enones or –Enals. Chen, Y.; Lu, Y.; Li, G.; Liu,* Y. Org. Lett. 2009, 11, 3838.

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