施世良 研究员(百人) 

  中国科学院上海有机化学研究所 

  金属有机化学国家重点实验室 

  上海市零陵路345号,200032 

  电话:021-54925580 

  电子邮箱:shiliangshi@sioc.ac.cn 

 

教育和工作经历: 

2016.06-至今       中国科学院上海有机化学研究所金属有机化学国家重点实验室, 研究员 

2012.11-2016.05    麻省理工学院化学系,博士后研究员(导师: Prof. Stephen L. Buchwald 

2011.10-2012.10    东京大学药学部, JSPS博士后研究员(导师: Prof. Motomu Kanai 

2008.10-2011.09    东京大学药学部, 博士(导师:Prof. Masakatsu Shibasaki and Prof. Motomu Kanai 

研究领域: 

1. 新颖高效实用有机合成方法学研究,侧重于手性合成和催化反应  

2. 新型功能聚合物的设计和合成 

获奖及荣誉: 

1. 国家优秀自费留学生奖2010年度  

2. 日本学术振兴会博士课程和博士后奖学金(DC2PD) 

3. 日本文部省奖学金    

职务: 

课题组长 

代表论著: 

1. Shi-Liang Shi, Zackary L. Wong, Stephen L. Buchwald “Copper-Catalyzed Enantioselective Stereodivergent Synthesis of Amino Alcohols” Nature 2016, 532, 353-356. 

2. Yang Yang#, Shi-Liang Shi#, Dawen Niu, Peng Liu, Stephen L. Buchwald “Catalytic Asymmetric Hydroamination of Unactivated Internal Olefins to Aliphatic Amines” Science 2015, 349, 62-66. (#: Co-first author) (Highlighted in Chemistry World and Chemical & Engineering News) 

3. Shi-Liang Shi, Stephen L. Buchwald “Copper-catalysed Selective Hydroamination Reactions of Alkynes” Nature Chemistry 2015, 7, 38-44.  (Highlighted in Nature. Nature 517, 280-281) 

4. Shi-Liang Shi, Stephen L. Buchwald “Palladium-Catalyzed Intramolecular C–H Difluoroalkylation: Synthesis of Substituted 3,3-Difluoro-2-oxindoles” Angew. Chem. Int. Ed. 2015, 54, 1646-1650. 

5. Shi-Liang Shi, Xiao-feng Wei, Yohei Shimizu, Motomu Kanai “Copper(I)-Catalyzed Enantioselective Incorporation of Ketones to Cyclic Hemiaminals for the Synthesis of Versatile Alkaloid Precursor” J. Am. Chem. Soc. 2012, 134, 17019-17022. 

6. Shi-Liang Shi, Motomu Kanai and Masakatsu Shibasaki “Asymmetric Synthesis of Dihydropyranones from Ynones by Sequential Copper(I)-Catalyzed Direct Aldol and Silver(I)-Catalyzed Oxy-Michael Reactions” Angew. Chem. Int. Ed. 2012, 51, 3932-3935. 

7. Shi-Liang Shi, Li-Wen Xu, Kounosuke Oisaki, Motomu Kanai and Masakatsu Shibasaki “Identification of Modular Chiral Bisphosphines Effective for Cu(I)-Catalyzed Asymmetric Allylation and Propargylation of Ketones” J. Am. Chem. Soc. 2010, 132, 6638-6639. 

8. Yohei Shimizu, Shi-Liang Shi, Hiroyuki Usuda, Motomu Kanai and Masakatsu Shibasaki “Catalytic Asymmetric Total Synthesis of ent-HyperforinAngew. Chem., Int. Ed. 2010, 49, 1103-1106.